British Air Force Typhoon FGR4s have conducted a mission with France's air force in a combined operation on an underground arms cache in Syrian territory used by the IS group, according to the UK Ministry of Defence.
The facility, identified by reconnaissance, was thought to be containing munitions and bombs, the announcement noted, and was situated in hills just to the north of the historic site of Palmyra in central Syria.
"Our fighter planes employed precision-guided Paveway IV munitions to hit a series of access tunnels leading to the depot... initial indications indicate the strike was effective," officials stated.
There was no sign of any civilian casualties in the attack on Saturday evening and every plane involved returned safely, the MoD added.
The British jets were supported by a Voyager refuelling tanker.
Daesh - alternatively referred to as the so-called Islamic State - imposed extremist governance over significant areas in Iraq and Syria until 2019.
"This operation underscores British leadership, and determination to stand shoulder to shoulder with our partners, to stamp out any re-emergence of Daesh and their violent and radical beliefs in the region," the British Defence Secretary John Healey stated.
RAF aircraft have carried out overwatch operations over Syrian airspace to "deter any efforts to regroup" of Islamic State after its defeat at the battle of Baghuz in 2019, the MoD reported.
"I must thank the personnel of British forces who took part in this operation for their professionalism and their courage," the Defence Secretary commented. "They were part of a great many British troops on duty over the holidays. This operation, to eliminate terrorist threats who pose a risk to our security, shows how our armed forces are prepared to act, all year round, ensuring Britain's security at home and influential overseas."
In December, the United States armed forces conducted what it described as a "massive strike" on IS targets in the country, following an attack resulted in the deaths of two US servicemembers and a local interpreter in Palmyra.
The U.N. says IS still has roughly 5-7 thousand combatants in both countries.